Equipment external dimensions:
Height 400 mm Width 250 mm Depth 255 mm
Equipment weight:
BRS system 8 Kg plus optional portable stand
Safety alarms:
High & Low temperature alarms
High & Low pressure alarm
Auto safety cut off
End of treatment alarm & auto stop
Electrical risk classification:
Class I, Type B
Fluid ingress protection:
IPX2
Function mode:
Continuous delivery at set temperature between 41 – 44°C ± 0.2 °C
Certification:
IEC/UL 60601-1; IEC 60601-1-2; IEC 60601-2; EN 55011; CAN/CSA-C22.2; CE0086
Equipment external dimensions:
Height 400 mm Width 250 mm Depth 255 mm
Equipment weight:
BRS system 9.6 Kg plus optional portable stand
Safety alarms:
High & Low temperature alarms
High pressure alarm
Auto safety cut off
End of treatment alarm & auto stop
Electrical risk classification:
Class I, Type B
Fluid ingress protection:
IPX2
Function mode:
Continuous delivery at set temperature between 41 – 44°C ± 0.5 °C
Certification:
UL 60601-1; IEC 60601-1-2; IEC 60601-2; EN 55011; CAN/CSA-C22.2; CE0086
The Combat BRS System is an innovative and patented recirculation system for the delivery of Hyperthermic Intra-VEsical Chemotherapy (HIVEC™). Hyperthermia has been shown to significantly increase the effectiveness of Mitomycin-C (MMC) in Non Muscle Invasive Bladder Cancer (NMIBC)1-2.
The Combat BRS System has been in clinical use since 2011, it is safe for patients and healthcare professionals, has similar patient tolerability to MMC at room temperature and is easy to use and adopt3.
The Combat BRS System uses an external dry conductive recirculation system. Our innovative and patented aluminium heat exchanger ensures efficient heat transfer and accurate temperature control within ± 0.5°C of the set temperature, whilst providing homogeneous drug and heat distribution throughout the bladder. Patient safety and comfort are paramount and the Combat BRS system has a range of safety features including; over temperature and high pressure audio and visual alarms as well as system auto cut off. At the end of a treatment the Combat BRS system also enables the removal of MMC from the patient for safe disposal.
The Combat BRS System harnesses accurate and effective heat control and the proven synergistic effects of chemo-hyperthermia to target NMIBC. The mutually enhancing effects of chemotherapy drugs and hyperthermia are well documented for their cytotoxic effects and are widely used in treating several types of cancer including bladder cancer4. Cancer cells become more permeable and are increasingly affected on many levels because of their inability to dissipate heat while the heat enhances the body’s natural immune responses5-7.
The Combat BRS System is portable, robust and easy to use. Simple to integrate into current treatment practice it requires minimal set up, no continuous monitoring and therefore minimal additional resources either physically, logistically or financially. Both the BRS system and disposable sets are affordable and through improving patient outcomes, the overall treatment cost can be reduced.
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